PUBMED

 

  
           
 

Fucoidan and Cancers

  1. Irhimeh MR, Fitton JH, Lowenthal RM.

    2. Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells.
    Exp Hematol. 2007 Jun;35(6):989-94. PMID: 17533053 [PubMed - indexed for MEDLINE]

  2. Cumashi A, Ushakova NA, Preobrazhenskaya ME, D'Incecco A, Piccoli A, Totani L, Tinari N, Morozevich GE, Berman AE, Bilan MI, Usov AI, Ustyuzhanina NE, Grachev AA, Sanderson CJ, Kelly M, Rabinovich GA, Iacobelli S, Nifantiev NE; Consorzio Interuniversitario Nazionale per la Bio-Oncologia, Italy.

    3. A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds.
    Glycobiology. 2007 May;17(5):541-52. Epub 2007 Feb 12. PMID: 17296677 [PubMed - indexed for MEDLINE]

  3. Tuddenham EG.

    4. Ways to bypass a blocked tenase complex.
    Thromb Haemost. 2006 Jan;95(1):1-2. No abstract available. PMID: 16543953 [PubMed - indexed for MEDLINE]

  4. Choi EM, Kim AJ, Kim YO, Hwang JK.

    5. Immunomodulating activity of arabinogalactan and fucoidan in vitro.
    J Med Food. 2005 Winter;8(4):446-53. PMID: 16379554 [PubMed - indexed for MEDLINE]

  5. Haneji K, Matsuda T, Tomita M, Kawakami H, Ohshiro K, Uchihara JN, Masuda M, Takasu N, Tanaka Y, Ohta T, Mori N.

    6. Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells.
    Nutr Cancer. 2005;52(2):189-201. PMID: 16201850 [PubMed - indexed for MEDLINE]

  6. Liu JM, Bignon J, Haroun-Bouhedja F, Bittoun P, Vassy J, Fermandjian S, Wdzieczak-Bakala J, Boisson-Vidal C.

    7. Inhibitory effect of fucoidan on the adhesion of adenocarcinoma cells to fibronectin.
    Anticancer Res. 2005 May-Jun;25(3B):2129-33. PMID: 16158954 [PubMed - indexed for MEDLINE]

  7. Aisa Y, Miyakawa Y, Nakazato T, Shibata H, Saito K, Ikeda Y, Kizaki M.

    8. Fucoidan induces apoptosis of human HS-sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways.
    Am J Hematol. 2005 Jan;78(1):7-14. PMID: 15609279 [PubMed - indexed for MEDLINE]

  8. Eichhorn ME, Strieth S, Krasnici S, Sauer B, Teifel M, Michaelis U, Naujoks K, Dellian M.

    9. Protamine enhances uptake of cationic liposomes in angiogenic microvessels.
    Angiogenesis. 2004;7(2):133-41. PMID: 15516834 [PubMed - indexed for MEDLINE]

  9. Mytar B, Woloszyn M, Macura-Biegun A, Hajto B, Ruggiero I, Piekarska B, Zembala M.

    10. Involvement of pattern recognition receptors in the induction of cytokines and reactive oxygen intermediates production by human monocytes/macrophages stimulated with tumour cells.
    Anticancer Res. 2004 Jul-Aug;24(4):2287-93. PMID: 15330174 [PubMed - indexed for MEDLINE]

  10. Maruyama H, Tamauchi H, Hashimoto M, Nakano T.

    11. Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida.
    In Vivo. 2003 May-Jun;17(3):245-9. PMID: 12929574 [PubMed - indexed for MEDLINE]

  11. Shibata H, Iimuro M, Uchiya N, Kawamori T, Nagaoka M, Ueyama S, Hashimoto S, Yokokura T, Sugimura T, Wakabayashi K.

    12. Preventive effects of Cladosiphon fucoidan against Helicobacter pylori infection in Mongolian gerbils.
    Helicobacter. 2003 Feb;8(1):59-65. PMID: 12603617 [PubMed - indexed for MEDLINE]

  12. Koyanagi S, Tanigawa N, Nakagawa H, Soeda S, Shimeno H.

    13. Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities.
    Biochem Pharmacol. 2003 Jan 15;65(2):173-9. PMID: 12504793 [PubMed - indexed for MEDLINE]

  13. Liu JM, Haroun-Bouhedja F, Boisson-Vidal C.

    14. Analysis of the in vitro inhibition of mammary adenocarcinoma cell adhesion by sulphated polysaccharides.
    Anticancer Res. 2000 Sep-Oct;20(5A):3265-71. PMID: 11062752 [PubMed - indexed for MEDLINE]

  14. Schaeffer DJ, Krylov VS.

    15. Anti-HIV activity of extracts and compounds from algae and cyanobacteria.
    Ecotoxicol Environ Saf. 2000 Mar;45(3):208-27. Review. PMID: 10702339 [PubMed - indexed for MEDLINE]

  15. Zugmaier G, Favoni R, Jaeger R, Rosen N, Knabbe C.

    16. Polysulfated heparinoids selectively inactivate heparin-binding angiogenesis factors.
    Ann N Y Acad Sci. 1999;886:243-8. PMID: 10667230 [PubMed - indexed for MEDLINE]

  16. Inoue M, Fujii H, Kaseyama H, Yamashina I, Nakada H.

    17. Stimulation of macrophages by mucins through a macrophage scavenger receptor.
    Biochem Biophys Res Commun. 1999 Oct 14;264(1):276-80. PMID: 10527877 [PubMed - indexed for MEDLINE]

  17. Shibata H, KimuraTakagi I, Nagaoka M, Hashimoto S, Sawada H, Ueyama S, Yokokura T.

    18. Inhibitory effect of Cladosiphon fucoidan on the adhesion of Helicobacter pylori to human gastric cells.
    J Nutr Sci Vitaminol (Tokyo). 1999 Jun;45(3):325-36. PMID: 10524351 [PubMed - indexed for MEDLINE]

  18. Brunner G, Reimbold K, Meissauer A, Schirrmacher V, Erkell LJ.

    19. Sulfated glycosaminoglycans enhance tumor cell invasion in vitro by stimulating plasminogen activation.
    Exp Cell Res. 1998 Mar 15;239(2):301-10. PMID: 9521847 [PubMed - indexed for MEDLINE]

  19. Yokota T, Ehlin-Henriksson B, Hansson GK.

    20. Scavenger receptors mediate adhesion of activated B lymphocytes.
    Exp Cell Res. 1998 Feb 25;239(1):16-22. PMID: 9511720 [PubMed - indexed for MEDLINE]

  20. Hsu HY, Hajjar DP, Khan KM, Falcone DJ.

    21. Ligand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway.
    J Biol Chem. 1998 Jan 9;273(2):1240-6. PMID: 9422792 [PubMed - indexed for MEDLINE]

  21. Stehle G, Sinn H, Wunder A, Schrenk HH, Schutt S, Maier-Borst W, Heene DL.

    22. The loading rate determines tumor targeting properties of methotrexate-albumin conjugates in rats.
    Anticancer Drugs. 1997 Aug;8(7):677-85. PMID: 9311444 [PubMed - indexed for MEDLINE]

  22. Matsumura K, Chiba A, Yamada H, Fukuta-Ohi H, Fujita S, Endo T, Kobata A, Anderson LV, Kanazawa I, Campbell KP, Shimizu T.

    23. A role of dystroglycan in schwannoma cell adhesion to laminin.
    J Biol Chem. 1997 May 23;272(21):13904-10. PMID: 9153251 [PubMed - indexed for MEDLINE]

  23. Incardona F, Lawler J, Cataldo D, Panet A, Legrand Y, Foidart JM, Legrand C.

    24. Heparin-binding domain, type 1 and type 2 repeats of thrombospondin mediate its interaction with human breast cancer cells.
    J Cell Biochem. 1996 Sep 15;62(4):431-42. PMID: 8891889 [PubMed - indexed for MEDLINE]

  24. Riou D, Colliec-Jouault S, Pinczon du Sel D, Bosch S, Siavoshian S, Le Bert V, Tomasoni C, Sinquin C, Durand P, Roussakis C.

    25. Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line.
    Anticancer Res. 1996 May-Jun;16(3A):1213-8. PMID: 8702239 [PubMed - indexed for MEDLINE]

  25. Itoh H, Noda H, Amano H, Ito H.

    26. Immunological analysis of inhibition of lung metastases by fucoidan (GIV-A) prepared from brown seaweed Sargassum thunbergii.
    Anticancer Res. 1995 Sep-Oct;15(5B):1937-47. PMID: 8572581 [PubMed - indexed for MEDLINE]

  26. Zhuang C, Itoh H, Mizuno T, Ito H.

    27. Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii).
    Biosci Biotechnol Biochem. 1995 Apr;59(4):563-7. PMID: 7772818 [PubMed - indexed for MEDLINE]

  27. Steuer MK, Steuer M, Bonkowsky V, Gabius HJ, Hofstadter F.

    28. Characterization of sugar receptor expression by neoglycoproteins in oral and oropharyngeal squamous cell carcinomas.
    Eur Arch Otorhinolaryngol. 1995;252(5):292-7. PMID: 7576587 [PubMed - indexed for MEDLINE]

  28. Vass JA, Csanaky G.

    29. Biotinylated L-selectin ligand analogs as cytochemical probes in cytospin preparations.
    Folia Histochem Cytobiol. 1995;33(1):39-41. PMID: 7556772 [PubMed - indexed for MEDLINE]

  29. Csanaky G, Vass JA, Ocsovszki I, Milosevits J, Szomor A, Schmelczer M.

    30. Changes in adhesion molecule expression and function in B-cell chronic lymphocytic leukaemia after in vitro interferon-alpha stimulation.
    Eur J Haematol. 1995 Jan;54(1):27-33. PMID: 7532138 [PubMed - indexed for MEDLINE]

  30. Soeda S, Ishida S, Shimeno H, Nagamatsu A.

    31. Inhibitory effect of oversulfated fucoidan on invasion through reconstituted basement membrane by murine Lewis lung carcinoma.
    Jpn J Cancer Res. 1994 Nov;85(11):1144-50. PMID: 7829400 [PubMed - indexed for MEDLINE]

  31. Soeda S, Ishida S, Honda O, Shimeno H, Nagamatsu A.

    32. Aminated fucoidan promotes the invasion of 3 LL cells through reconstituted basement membrane: its possible mechanism of action.
    Cancer Lett. 1994 Sep 30;85(1):133-8. PMID: 7923097 [PubMed - indexed for MEDLINE]

  32. Kobayashi T, Honke K, Miyazaki T, Matsumoto K, Nakamura T, Ishizuka I, Makita A.

    33. Hepatocyte growth factor specifically binds to sulfoglycolipids.
    J Biol Chem. 1994 Apr 1;269(13):9817-21. PMID: 8144574 [PubMed - indexed for MEDLINE]

  33. Itoh H, Noda H, Amano H, Zhuaug C, Mizuno T, Ito H.

    34. Antitumor activity and immunological properties of marine algal polysaccharides, especially fucoidan, prepared from Sargassum thunbergii of Phaeophyceae.
    Anticancer Res. 1993 Nov-Dec;13(6A):2045-52. PMID: 8297113 [PubMed - indexed for MEDLINE]

  34. Csanaky G, Vass JA, Losonczy H, Schmelczer M.

    35. Expression of an adhesion molecule and homing in B-cell chronic lymphocytic leukaemia: II. L-selectin expression mediated cell adhesion revealed by immobilized analogue carbohydrates in B-cell chronic lymphocytic leukaemia and monoclonal lymphocytosis of undetermined significance.
    Med Oncol Tumor Pharmacother. 1993;10(4):173-80. PMID: 8164454 [PubMed - indexed for MEDLINE]

  35. Takahashi N, Machiguchi Y, Sato N, Ohnishi R, Nishikawa K, Wada Y, Cho JM, Miyake H, Kikuchi K.

    36. [Acquisition of contact inhibition in ras-oncogene transformant by fucoidan from marine algae]
    Gan To Kagaku Ryoho. 1992 Mar;19(3):405-7. Japanese. No abstract available. PMID: 1543369 [PubMed - indexed for MEDLINE]

  36. Steuer MK, Gabius HJ, Bardosi A, Matthias R.

    37. [Histochemical identification of endogenous lectins using labelled neoglycoproteins in human head-and-neck squamous cell carcinoma]
    Laryngorhinootologie. 1991 May;70(5):243-9. Review. German. PMID: 2064700 [PubMed - indexed for MEDLINE]

  37. Harris JF, Beaton DW.

    38. Sulfated glycoconjugate determinants recognized by monoclonal antibody, SG-1, correlate with the experimental metastatic ability of KHT fibrosarcoma cells.
    Clin Exp Metastasis. 1990 Jul-Aug;8(4):361-79. PMID: 1693555 [PubMed - indexed for MEDLINE]

  38. Roszkowski W, Beuth J, Ko HL, Uhlenbruck G, Pulverer G.

    39. Blocking of lectin-like adhesion molecules on pulmonary cells inhibits lung sarcoma L-1 colonization in BALB/c-mice.
    Experientia. 1989 Jun 15;45(6):584-8. PMID: 2737266 [PubMed - indexed for MEDLINE]

  39. Kayser K, Gabius HJ, Ciesiolka T, Ebert W, Bach S.

    40. Histopathologic evaluation of application of labeled neoglycoproteins in primary bronchus carcinoma.
    Hum Pathol. 1989 Apr;20(4):352-60. PMID: 2467870 [PubMed - indexed for MEDLINE]

  40. Roberts DD.

    41. Interactions of thrombospondin with sulfated glycolipids and proteoglycans of human melanoma cells.
    Cancer Res. 1988 Dec 1;48(23):6785-93. PMID: 3180088 [PubMed - indexed for MEDLINE]

  41. Ginsburg V, Roberts DD.

    42. Glycoconjugates and cell adhesion: the adhesive proteins laminin, thrombospondin and von Willebrand's factor bind specifically to sulfated glycolipids.
    Biochimie. 1988 Nov;70(11):1651-9. Review. PMID: 3149529 [PubMed - indexed for MEDLINE]

  42. Roberts DD, Wewer UM, Liotta LA, Ginsburg V.

    43. Laminin-dependent and laminin-independent adhesion of human melanoma cells to sulfatides.
    Cancer Res. 1988 Jun 15;48(12):3367-73. PMID: 2967105 [PubMed - indexed for MEDLINE]

  43. Mizumoto K, Sugawara I, Ito W, Kodama T, Hayami M, Mori S.

    44. Sulfated homopolysaccharides with immunomodulating activities are more potent anti-HTLV-III agents than sulfated heteropolysaccharides.
    Jpn J Exp Med. 1988 Jun;58(3):145-51. PMID: 2903262 [PubMed - indexed for MEDLINE]

  44. Taraboletti G, Roberts DD, Liotta LA.

    45. Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains.
    J Cell Biol. 1987 Nov;105(5):2409-15. PMID: 3680388 [PubMed - indexed for MEDLINE]

  45. Maruyama H, Nakajima J, Yamamoto I.

    46. A study on the anticoagulant and fibrinolytic activities of a crude fucoidan from the edible brown seaweed Laminaria religiosa, with special reference to its inhibitory effect on the growth of sarcoma-180 ascites cells subcutaneously implanted into mice.
    Kitasato Arch Exp Med. 1987 Sep;60(3):105-21. No abstract available. PMID: 2455094 [PubMed - indexed for MEDLINE]

  46. Chida K, Yamamoto I.

    47. Antitumor activity of a crude fucoidan fraction prepared from the roots of kelp (Laminaria species).
    Kitasato Arch Exp Med. 1987 Jun;60(1-2):33-9. No abstract available. PMID: 3669501 [PubMed - indexed for MEDLINE]

  47. Coombe DR, Parish CR, Ramshaw IA, Snowden JM.

    48. Analysis of the inhibition of tumour metastasis by sulphated polysaccharides.
    Int J Cancer. 1987 Jan 15;39(1):82-8. PMID: 2878892 [PubMed - indexed for MEDLINE]

  48. Roberts DD, Sherwood JA, Ginsburg V.

    49. Platelet thrombospondin mediates attachment and spreading of human melanoma cells.
    J Cell Biol. 1987 Jan;104(1):131-9. PMID: 3793757 [PubMed - indexed for MEDLINE]

  49. Hashimoto S, Nomoto K, Nagaoka M, Yokokura T.

    50. In vitro and in vivo release of cytostatic factors from Lactobacillus casei-elicited peritoneal macrophages after stimulation with tumor cells and immunostimulants.
    Cancer Immunol Immunother. 1987;24(1):1-7. PMID: 3102062 [PubMed - indexed for MEDLINE]

  50. Via DP, Plant AL, Craig IF, Gotto AM Jr, Smith LC.

    51. Metabolism of normal and modified low-density lipoproteins by macrophage cell lines of murine and human origin.
    Biochim Biophys Acta. 1985 Mar 6;833(3):417-28. PMID: 3855661 [PubMed - indexed for MEDLINE]

  51. Yamamoto I, Takahashi M, Suzuki T, Seino H, Mori H.

    52. Antitumor effect of seaweeds. IV. Enhancement of antitumor activity by sulfation of a crude fucoidan fraction from Sargassum kjellmanianum.
    Jpn J Exp Med. 1984 Aug;54(4):143-51. PMID: 6513098 [PubMed - indexed for MEDLINE]

  52. Teas J, Harbison ML, Gelman RS.

    53. Dietary seaweed (Laminaria) and mammary carcinogenesis in rats.
    Cancer Res. 1984 Jul;44(7):2758-61. PMID: 6426785 [PubMed - indexed for MEDLINE]

  53. Sugawara I, Lee KC.

    54. Fucoidan blocks macrophage activation in an inductive phase but promotes macrophage activation in an effector phase.
    Microbiol Immunol. 1984;28(3):371-7. PMID: 6429485 [PubMed - indexed for MEDLINE]

  54. Grabel LB, Singer MS, Martin GR, Rosen SD.

    55. Teratocarcinoma stem cell adhesion: the role of divalent cations and a cell surface lectin.
    J Cell Biol. 1983 Jun;96(6):1532-7. PMID: 6406515 [PubMed - indexed for MEDLINE]

  55. Grabel LB, Glabe CG, Singer MS, Martin GR, Rosen SD.

    56. A fucan specific lectin on teratocarcinoma stem cells.
    Biochem Biophys Res Commun. 1981 Oct 30;102(4):1165-71. No abstract available. PMID: 7317046 [PubMed - indexed for MEDLINE]

 

    
 
   
 
 
 
 
   
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